furafylline (Toronto Research Chemicals)
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furafylline
Furafylline, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/furafylline/Furafylline/pm38914316-49-98-106
Average 92 stars, based on 1 article reviews
Furafylline, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/furafylline/Furafylline/pm38914316-49-98-106
Average 92 stars, based on 1 article reviews
furafylline - by Bioz Stars,
2026-10
92/100 stars
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Incubation:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Blocking Assay:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Control:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Solvent:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Liquid Chromatography with Mass Spectroscopy:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Comparison:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Software:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Two Tailed Test:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Inhibition:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( Activity Assay:Article Title: Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib Article Snippet: Data were fit to the following equation using nonlinear regression analysis with GraphPad Prism 9.0 software to estimate the apparent K I and k inact . Article Title: Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions. Article Snippet: Vicagrel, an antiplatelet drug candidate targeting platelet P2Y12 receptor and has finished its phase II clinical trial.. The inhibition of six major cytochrome P450 enzymes (P450) (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) and six UDP-glucuronosyltransferases (UGT) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, and UGT2B7) by vicagrel was evaluated using pooled human liver microsomes and specific probe substrates.. Physiology-based pharmacokinetic (PBPK) simulation was further applied to predict the in vivo drugdrug interaction (DDI) potential between vicagrel and bupropion as well as S-mephenytoin. Article Title: Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation Article Snippet: N -Desethylsunitinib (D289650), Article Title: Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats. Article Snippet: Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity.. However, its metabolism and disposition are little known.. In this study, we investigated the metabolic characteristics of dendrobine in vitro and in rats. Article Title: Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol. Article Snippet: Furafylline, 2-phenyl-2-(1piperidinyl)propane, CYP3cide, and ( |
